Classification of Human Blood Plasma Lipid Abnormalities by 1H Magnetic Resonance Spectroscopy and Self-Organizing Maps
Yrj| Hiltunen, The Raahe Institute of Computer Engineering, Pehr Brahe Laboratory, Raahe, Finland,
Jouni Kaartinen, The Raahe Institute of Computer Engineering, Pehr Brahe Laboratory, Raahe, Finland,
Mika Ala-Korpela, University of Kuopio, A. I. Virtanen Institute for Molecular Sciences
Email: yrjo.hiltunen@ratol.fi
Abstract:
Magnetic resonance spectroscopy (MRS) is increasing used
in biomedical and clinical studies. Analysis of the MRS data is
not straightforward due to complex systems and also partly
unknown underlying biochemistry. Here we demonstrate
how self-organizing maps (SOM) can be utilised in biomedical MRS.
Their modelling power is illustrated by establishing lipoprotein lipid
classification directly from 1H MR spectra of human blood plasma.
WSOM'97